Tamoxifen is a selective estrogen receptor modulator (SERM) primarily used for PCT and prevention/treatment of gynecomastia. It works by blocking estrogen receptors in breast tissue while allowing estrogen to function normally in other tissues like bone and liver.
As a PCT medication, tamoxifen stimulates the release of LH and FSH from the pituitary gland, helping to restart natural testosterone production after a steroid cycle. It’s generally preferred over Clomiphene for most users due to fewer mood-related side effects and better tolerance.
Tamoxifen can also be used during cycle for gynecomastia prevention, though modern [aromatase] inhibitors are generally preferred for estrogen control. The compound has a long half-life, allowing for once-daily dosing, and is generally well-tolerated with minimal side effects.