Aromasin

Exemestane is a steroidal AI that permanently binds to and destroys the [aromatase] enzyme. Unlike reversible [AIs] like Anastrozole, exemestane’s effects persist even after discontinuation until new [aromatase] enzymes are produced.

This ‘suicidal’ mechanism makes exemestane particularly effective for estrogen control, but also makes it easier to crash estrogen levels if overdosed. Many users prefer exemestane because it has less negative impact on lipids compared to other [AIs] and may have mild androgenic effects.

Exemestane is often preferred during PCT as it doesn’t interfere with the beneficial effects of [SERMs] like Tamoxifen, unlike reversible [AIs] which can reduce SERM effectiveness.